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Home / Antibodies

COX2 Antibody / PTGS2 (V8038)

SKU : BHA17117422

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NSJ Bioreagents

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Mfr.No.	V8038, V8038-20UG, V8038-100UG
Antigen	COX2
Clonality	Monoclonal
Description	Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general housekeeping functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs. COX2 expression is significantly increased in 85-90% of human colorectal adenocarcinomas whereas levels of COX-1 are not changed.
Formulation	0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	A recombinant human partial protein (amino acids 442-572) was used as the immunogen for the COX2 antibody.
Isotype	IgG2b,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P35354
Clone No	COX2/1941

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the COX2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	ELISA, WB
Dilution	ELISA (order BSA-free format for coating),Western blot: 1-2ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17117422-1	V8038-20UG	20ug	$219		Add to Cart
BHA17117422-2	V8038-100UG	100ug	$499		Add to Cart

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