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Home / Primary Antibodies / Polyclonal Antibodies

CHCHD3 antibody

SKU : BHA10801631

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Mfr.No.	FNab01636
Alternative Names	MIC19 ; MINOS3
Background	The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS). Several transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:25781180).
Host	Rabbit
Immunogen	coiled-coil-helix-coiled-coil-helix domain containing 3
Isotype	IgG
Molecular Weight	30 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	MIC19, MINOS3

Uniprot	Q9NX63
Gene Id	54927
Research Area	Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab01636.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801631	FNab01636	100ug	$260		Add to Cart

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