Rabbit Anti-Human CDK7 (pThr170) Polyclonal

Mfr.No.	SPC-945, SPC-945D, SPC-945D-A390, SPC-945D-A488, SPC-945D-A594, SPC-945D-BI, SPC-945D-FITC
Immunogen Species	Human
Alternative Names	39 kDa protein kinase Antibody, CAK Antibody, CAK1 Antibody, Cdk activating kinase Antibody, CDK7_HUMAN Antibody, Cell division protein kinase 7 Antibody, Cyclin dependent kinase 7 Antibody, HCAK Antibody, MO15 Antibody, P39 Mo15 Antibody, Serine threonine kinase Stk1 Antibody, STK1 Antibody, TFIIH basal transcription factor complex kinase subunit Antibody
Antigen	CDK7
Categories	Antibodies
Cellular Localization	Nucleus
Certificate Of Analysis	A 1:250 dilution of SPC-945 was sufficient for detection of CDK7 (pThr170) in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Conjugate	Unconjugated, ATTO 390, ATTO 488, ATTO 594, Biotin, FITC
Description	Rabbit Anti-Human CDK7 (pThr170) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Thr170 of human CDK7 (AA167-173), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Thr170 of human CDK7 (AA167-173)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Ubiquitous

Swissprot	P50613
Accession Number	NP_001790
Gene Id	1022
Target	CDK7 (pThr170)
Research Area	Cell Signaling, Epigenetics and Nuclear Signaling, Protein Phosphorylation, Cdks

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Ubiquitous
Scientific Background	CDK7 is a protein-serine/threonine kinase. CDK7 has been identified as the mammalian homolog of MO15, a protein kinase demonstrated in starfish and Xenopus. The regulatory subunit is a novel cyclin (cyclin H) and is required for activation of CDK7. Like other Cdks, CDK7 contains a conserved threonine residue required for full activity; mutation of this residue severely reduces CAK activity.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~39kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11911826-1	SPC-945D	Unconjugated	100 ul	$331	Add to Cart
BHA11911826-2	SPC-945D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11911826-3	SPC-945D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11911826-4	SPC-945D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11911826-5	SPC-945D-BI	Biotin	100 ul	$380	Add to Cart
BHA11911826-6	SPC-945D-FITC	FITC	100 ul	$375	Add to Cart

CDK7 Antibody (pThr170) - SPC-945