Binder of Rho GTPases 2; BORG2; CDC42 effector protein (Rho GTPase binding) 3; Cdc42 effector protein 3; CDC42EP3
Antigen
Cdc42EP3
Categories
Primary Antibodies
Clonality
polyclonal
Description
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.Joberty G., Mol. Cell. Biol. 19:6585-6597(1999).Hirsch D.S., J. Biol. Chem. 276:875-883(2001).Wiemann S., Genome Res. 11:422-435(2001).
Host
Rabbit
Immunogen
Synthesized peptide derived from N-terminal of Human CDC42EP3.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
Protein Families
BORG/CEP family
Tissue Specificity
Highly expressed in the heart and weakly in the brain.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.