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Home / Antibodies

CD63 Antibody / LAMP3 (V3028)

SKU : BHA17113192

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NSJ Bioreagents

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Mfr.No.	V3028, V3028-20UG, V3028-100UG
Antigen	CD63
Clonality	Monoclonal
Description	This mAb recognizes protein of 26kDa-60kDa, which is identified as CD63/LAMP-3. Its epitope is different from that of mAb LAMP3/803 or LAMP3/968 or NKI/C3 or MX-49.129.5. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63/LAMP-3 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. It is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63/LAMP-3 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. Deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Mouse
Immunogen Region	Recombinant human protein was used as the immunogen for the LAMP-3 antibody.
Isotype	IgG2a,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cytoplasmic

Uniprot	P08962
Clone No	LAMP3/529

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the LAMP-3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	ELISA, FACS, IF
Dilution	ELISA (order BSA/sodium azide-free format for coating),Flow cytometry: 1-2ug/million cells,Immunofluorescence: 0.5-1ug/ml

Product Manual	Data Sheet

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17113192-1	V3028-20UG	20ug	$219		Add to Cart
BHA17113192-2	V3028-100UG	100ug	$499		Add to Cart

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