Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1(PubMed:2214026, PubMed:16331979, PubMed:9641677). Down-regulated by HIV-1 Vpu(PubMed:17346169). Acts as a receptor for Human Herpes virus 7/HHV-7(PubMed:7909607).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1 (PubMed:2214026, PubMed:16331979, PubMed:9641677). Down-regulated by HIV-1 Vpu (PubMed:17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed:7909607).
Host
Rabbit
Immunogen
CD4 molecule
Isotype
IgG
Molecular Weight
55 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Uniprot
P01730
Gene Id
920
Research Area
Developmental biology, Cancer, Immunology, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)