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Home / Primary Antibodies / Polyclonal Antibodies

CD320 antibody

SKU : BHA10801461

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Mfr.No.	FNab01466
Alternative Names	8D6A
Background	CD320, also known as 8D6, 8D6A or TCblR, is a single-pass type I membrane protein containing 2 LDL-receptor class A domains. Expressed abundantly on follicular dendritic cells (FDCs), CD320 has been shown to enhance proliferation of germinal center (GC) B cells. It is the receptor for cellular uptake of transcobalamin-bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC). CD320 has a calculated molecular mass of 29 kDa. This antibody detects bands at 50-55 kDa and 60-70 kDa, probably caused by extensive complex glycosylation.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin.
Host	Rabbit
Immunogen	CD320 molecule
Isotype	IgG
Molecular Weight	50-55 kDa, 60-70 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	8D6, 8D6 antigen, 8D6A, CD320, CD320 antigen, CD320 molecule, FDC signaling molecule 8D6, FDC SM 8D6, TCblR, Transcobalamin receptor

Uniprot	Q9NPF0
Gene Id	51293
Research Area	Developmental biology, Immunology

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:1000; IHC: 1:20-1:200

Manual	FNab01466.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801461	FNab01466	100ug	$240		Add to Cart

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