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Home / Primary Antibodies / Monoclonal Antibodies

Cav3.1 Antibody, Clone S178A-9 - SMC-405

BHA11903602
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+1 866.986.9598
Email
[email protected]
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Swissprot Q9WUT2
Accession Number NP_001106284.1
Gene Id 12291
Target Cav3.1
Clone No S178A-9
Research Area Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels, Neuroscience
Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration 1 mg/ml
Dilutions WB (1:1000), ICC/IF (1:100);optimal dilutions for assays should be determined by the user.
Purification Protein G Purified
Scientific Background Calcium channel CaV3.1 (a1G) is a low-voltage-activated T-type calcium channel. Such T-type channels are expressed throughout the body. In the heart, they may be involved in pacemaker current. In neurons, these channels may play a secondary pacemaker role (1). With the ubiquitous expression, it is not surprising that alterations in channel function have been implicated in disease. Drugs that act to block T-type calcium channels are used as anti-hypertensives, antiepileptic's, and blocking of T-type calcium channels may be involved in the action of some anesthetics and antipsychotics as well (1). Much remains to be determined about the precise cellular localization, in vivo physiological roles, roles in disease states and possible routes to modulate their structure/function to ameliorate effects of disease.
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~<200kDa. Does not cross-react with Cav3.2.
Storage -20ºC
Storage Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications IHC, WB, ICC/IF
Description WB ; IHC ; ICC ; IF
Dilution WB (1:1000), ICC/IF (1:100);optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Perez-Reyes E. (2003). Physiol. Rev., 83: 117-161.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11903602-1 SMC-405D Unconjugated 100 ug $330
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BHA11903602-2 SMC-405D-A390 ATTO 390 100 ug $384
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BHA11903602-3 SMC-405D-A488 ATTO 488 100 ug $383
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BHA11903602-4 SMC-405D-A594 ATTO 594 100 ug $383
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BHA11903602-5 SMC-405D-ALP Alkaline Phosphatase 100 ug $376
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BHA11903602-6 SMC-405D-APC APC 100 ug $382
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BHA11903602-7 SMC-405D-BI Biotin 100 ug $378
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BHA11903602-8 SMC-405D-FITC FITC 100 ug $374
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BHA11903602-9 SMC-405D-HRP HRP 100 ug $370
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BHA11903602-10 SMC-405D-PCP PerCP 100 ug $382
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BHA11903602-11 SMC-405D-RPE RPE 100 ug $380
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BHA11903602-12 SMC-405S Unconjugated 12 ug $44
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