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Home / Primary Antibodies

Caspase-8 Antibody (R30365)

SKU : BHA17104057

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NSJ Bioreagents

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Mfr.No.	R30365
Clonality	Polyclonal
Description	Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases including CASP3/4/6/7/9/10. (UniProt)
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids 240-259 (DKVYQMKSKPRGYCLIINNH-human) were used as the immunogen for this anti-Caspase-8 antibody. This sequence is from the large subunit.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Uniprot	Q14790

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the anti-Caspase-8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104057	R30365	100 ug	$419		Add to Cart

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