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Home / Antibodies

Caldesmon / CAD Antibody HMW (V7200IHC)

SKU : BHA17126130

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NSJ Bioreagents

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Mfr.No.	V7200IHC-7ML
Clonality	Recombinant Rabbit Monoclonal
Description	Caldesmon is an actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity). (UniProt)
Formulation	Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; For IHC use only
Host	Rabbit
Immunogen Region	A full length human protein was used as the immunogen for the recombinant CAD antibody.
Isotype	Rabbit IgG, kappa
Species Reactivity	Human
Note	Titering of the recombinant CAD antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Uniprot	Q05682

Format	Purified
Purity	Protein A affinity chromatography
Storage	Store the recombinant CAD antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17126130	V7200IHC-7ML	7 ml	$499		Add to Cart

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