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Home / Primary Antibodies / Polyclonal Antibodies

c-MYC antibody

SKU : BHA10810297

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Mfr.No.	FNab10342
Background	MYC contains one basic helix-loop-helix(bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC(GA)TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC (PMID: 12189186)
Clonality	polyclonal
Host	Rabbit
Immunogen	v-myc myelocytomatosis viral oncogene homolog(avian)
Immunogen Region	v-myc myelocytomatosis VIral oncogene homolog(aVIan)
Isotype	IgG
Molecular Weight	50-60 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500-1:2000
Synonyms	BHLHe39, c Myc, c-Myc, MRTL, MYC, Myc proto oncogene protein, Proto oncogene c Myc, Transcription factor p64

Uniprot	P01106
Research Area	Epigenetics, Cell Division and Proliferation, Metabolism, Immunology, Cancer, Stem Cells, Neuroscience

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10342.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810297	FNab10342	100ug	$240		Add to Cart

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