Rabbit Anti-Human BRCA1 (pSer1423) Polyclonal

Mfr.No.	SPC-1353, SPC-1353D, SPC-1353D-A390, SPC-1353D-A488, SPC-1353D-A594, SPC-1353D-BI, SPC-1353D-FITC
Immunogen Species	Human
Alternative Names	BRCAI Antibody, EC:2.3.2.27 Antibody, BRCA 1 Antibody, BRCC1 Antibody, Protein phosphatase 1 regulatory subunit 53 Antibody, BRCA1 Antibody, BRCA1 DNA repair associated Antibody, FANCS Antibody, PPP1R53 Antibody, PNCA4 Antibody, Breast cancer type 1 susceptibility protein Antibody, BROVCA1 Antibody, RING finger protein 53 Antibody, Breast and ovarian cancer susceptibility protein 1 Antibody, RING-type E3 ubiquitin transferase BRCA1 Antibody, RNF53 Antibody, Breast Cancer 1 Antibody, Breast Cancer 1 Early Onset Antibody, BRCA1/BRCA2 containing complex subunit 1 Antibody, BRCA1_HUMAN Antibody, PSCP Antibody, BRCA1/BRCA2-containing complex, subunit 1 Antibody, IRIS Antibody, BRCC 1 Antibody
Antigen	BRCA1
Categories	Antibodies
Cellular Localization	Cytoskeleton, Nucleus, Chromosome, Cytoplasm, Gamma-Tubulin Ring Complex, Brca1-A Complex, Brca1-Bard1 Complex, Lateral Element, Nucleoplasm, Plasma Membrane, Intracellular Ribonucleoprotein Complex, Protein Complex, Ubiquitin Ligase Complex
Clonality	Polyclonal
Conjugate	Unconjugated, ATTO 390, ATTO 488, ATTO 594, Biotin, FITC
Description	Rabbit Anti-Human BRCA1 (pSer1423) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic phospho-peptide from human BRCA1 around the phosphorylation site of serine 1423 (pSer1423)., Homo Sapiens (Human)
Immunogen Region	Synthetic phospho-peptide from human BRCA1 around the phosphorylation site of serine 1423 (pSer1423).
Launch Date	2018/03/07
Net Weight (g)	0.1
Reactivity	Rat, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Rat, Human
Tissue Specificity	Isoform 1 and isoform 3 are widely expressed. Isoform 3 is reduced or absent in several breast and ovarian cancer cell lines.

Swissprot	P38398
Accession Number	NP_009225.1
Gene Id	672
Target	BRCA1 (pSer1423)
Research Area	Cell Signaling, Epigenetics and Nuclear Signaling, DNA/RNA, DNA Damage and Repair, Chromatin Modifying Enzymes, Chromatin Ubiquitination, Post-translational Modifications, Ubiquitination, E3 Ubiquitin Ligases, Cancer, Tumor suppressors, BRAC1

Buffer	PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide
Dilutions	WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:2500); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Isoform 1 and isoform 3 are widely expressed. Isoform 3 is reduced or absent in several breast and ovarian cancer cell lines.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects endogenous levels of BRCA1 protein only when phosphorylated at serine 1423 (pSer1423). Detects a band at ~210 kDa.
Storage	-20ºC
Storage Buffer	PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	ELISA, IHC, WB
Description	WB ; IHC ; ELISA
Dilution	WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:2500); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11918540-1	SPC-1353D	Unconjugated	100 ul	$331	Add to Cart
BHA11918540-2	SPC-1353D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11918540-3	SPC-1353D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11918540-4	SPC-1353D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11918540-5	SPC-1353D-BI	Biotin	100 ul	$380	Add to Cart
BHA11918540-6	SPC-1353D-FITC	FITC	100 ul	$375	Add to Cart

BRCA1 Antibody (pSer1423) - SPC-1353

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