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Home / Primary Antibodies / IHC Antibodies

BAX Antibody

SKU : BHA10559410

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA552355
Alternative Names	BAX protein; cytoplasmic isoform delta; BAX;
Categories	Primary Antibodies
Clonality	polyclonal
Description	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.Apte S.S., Genomics 26:592-594(1995).Guo B., Nature 423:456-461(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human BAX.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. Apte S.S., Genomics 26:592-594(1995). Guo B., Nature 423:456-461(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total BAX protein.

Uniprot	P55269

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC, IF

Description

ELISA ; IHC ; IF, IF ; ELISA ; IHC

Dilution

IHC	1:50-1:100
IF	1:100-1:500

Tested Application

ELISA,IHC,IF;IHC:1:50-1:100,IF:1:100-1:500

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559410	CSB-PA552355	100ul	$297		Add to Cart

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