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Home / Primary Antibodies / Polyclonal Antibodies

ATP1A1 antibody

SKU : BHA10800686

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Mfr.No.	FNab00691
Background	The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Host	Rabbit
Immunogen	ATPase, Na+/K+ transporting, alpha 1 polypeptide
Isotype	IgG
Molecular Weight	113 kDa
Reactivity	Human, Mouse, Rat, Rabbit, Pig, Monkey, Zebrafish, Hamster
Regulatory	RUO
Synonyms	ATP1A1, Na(+)/K(+) ATPase 1, Na(+)/K(+) ATPase alpha 1 subunit, Na+/K+ ATPase 1, Sodium potassium ATPase alpha 1 polypeptide, Sodium pump subunit alpha 1

Uniprot	P05023
Gene Id	476
Research Area	Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IP, IHC, WB
Description	ELISA ; IP ; IHC ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:500

Manual	FNab00691.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800686	FNab00691	100ug	$240		Add to Cart

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