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Home / Antibodies

ARHGEF1 Antibody

BHA10543864
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+1 866.986.9598
Email
[email protected]
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Rgd 620951
Target Details Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Uniprot Q92888
Gene Id 9138
Database Links

HGNC:681

OMIM:601855

KEGG:hsa:9138

STRING:9606.ENSP00000337261

UniGene:Hs.631550
Function Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
Pathway Regulation of actin cytoskeleton Vascular smooth muscle contraction
Tissue Specificity Ubiquitously expressed.
Weight 104,066 Da
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles.
Format Liquid
Purification Antigen Affinity Purified
Purity Antigen Affinity Purified
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Applications ELISA, WB
Description ELISA ; WB, WB ; ELISA
Tested Application ELISA,WB
Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
SKU Supplier No. Size Your price Quantity
BHA10543864 CSB-PA002040GA01HU 150μl $610.56
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BHA10543864 CSB-PA002040GA01HU 50μl $269.50
Add to Cart