JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.
Loding Loading ....
Home / Primary Antibodies / Polyclonal Antibodies

Aquaporin 2 Antibody - SPC-503

BHA11907900
Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
Request More Infos
Order Now

Credit card payments now incur a 3% fee.

Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
Ask Merchant
Request More Infos
Sample Request
Swissprot P34080
Accession Number NP_037041.2
Gene Id 25386
Target Aquaporin 2
Research Area Neurotransmission, Ion Channels, Aquaporins, Neuroscience
Buffer PBS, 50% glycerol, 0.09% sodium azide
Concentration 1 mg/ml
Dilutions WB (1:2000), IHC (1:200), ICC/IF (1:400); optimal dilutions for assays should be determined by the user.
Purification Protein A Purified
Scientific Background Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquaporin 2 is the vasopressin-regulated water channel of the apical membrane of collecting duct cells. It is located in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes. When it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that cause AQP2 containing vesicles to fuse with the plasma membrane so the AQP2 can be used by the cell (3). Defects in AQP2 area cause of an autosomal dominant form of nephrogenic diabetes insipidus (NDI) (4).
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~28.8kDa. May detect larger glycosylated bands ~35-50kDa.
Storage -20ºC
Storage Buffer PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications IHC, WB, ICC/IF
Description WB ; IHC ; ICC ; IF
Dilution WB (1:2000), IHC (1:200), ICC/IF (1:400); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Gonen T., Walz T. (2006) Q. Rev. Biophys. 39(4): 361-396.

2. Knepper M.A. (1994) Proc Natl. Acad Sci. USA. 91(14): 6255-6258.

3. Lodish H.F. (2008) Molecular Cell Biology. New York: W.H. Freeman. Print. 445.

4. www.vivo.colostate.edu/hbooks/molecules/aquaporins.html
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11907900-1 SPC-503D Unconjugated 100 ug $330
Add to Cart
BHA11907900-2 SPC-503D-A390 ATTO 390 100 ug $384
Add to Cart
BHA11907900-3 SPC-503D-A488 ATTO 488 100 ug $383
Add to Cart
BHA11907900-4 SPC-503D-A594 ATTO 594 100 ug $383
Add to Cart
BHA11907900-5 SPC-503D-ALP Alkaline Phosphatase 100 ug $376
Add to Cart
BHA11907900-6 SPC-503D-APC APC 100 ug $382
Add to Cart
BHA11907900-7 SPC-503D-BI Biotin 100 ug $378
Add to Cart
BHA11907900-8 SPC-503D-FITC FITC 100 ug $374
Add to Cart
BHA11907900-9 SPC-503D-HRP HRP 100 ug $370
Add to Cart
BHA11907900-10 SPC-503D-PCP PerCP 100 ug $382
Add to Cart
BHA11907900-11 SPC-503D-RPE RPE 100 ug $380
Add to Cart
BHA11907900-12 SPC-503S Unconjugated 12 ug $44
Add to Cart