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Home / Primary Antibodies / Polyclonal Antibodies

APTX antibody

SKU : BHA10810317

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Mfr.No.	FNab10359
Background	APTX, also named as Aprataxin, is a nuclear protein, present in both the nucleoplasm and the nucleolus, which is a member of the histidine triad (HIT) superfamily. APTX is involved in DNA single-strand break repair, mediating protein-protein interactions with molecules responding to DNA damage. APTX contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain. Loss of function mutations in APTX, the gene encoding for Aprataxin, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, characterized by abnormal movements of the head and eyes.
Clonality	polyclonal
Host	Rabbit
Immunogen	aprataxin
Immunogen Region	endomucin
Isotype	IgG
Molecular Weight	40 kDa
Reactivity	Human
Recommended Dilution	WB: 1:500-1:2000
Synonyms	AOA, AOA1, aprataxin, APTX, AXA1, EAOH, EOAHA, FHA HIT

Uniprot	Q7Z2E3
Gene Id	54840

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:2000; IHC: 1:20 - 1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10350.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810317	FNab10359	100ug	$240		Add to Cart

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