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Home / Antibodies

Anti-USP11 Antibody BHA11303172

SKU : BHA11303172

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Mfr.No.	BS5973
Alternative Names	Ubiquitin carboxyl-terminal hydrolase 11 ; Deubiquitinating enzyme 11 ; Ubiquitin thioesterase 11 ; Ubiquitin-specific-processing protease 11 ; UHX1
Categories	Primary Antibodies
Chromosome Location	Xp11.3
Clonality	polyclonal
Description	USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the Ub pathway. Localized to the nucleus, USP11 associates with both Ran BP-M (Ran binding protein M) and with the tumor suppressor BRCA2. Through these associations, USP11 functions to either inhibit ubiquitination of these proteins or to remove ubiquitin residues that have already been attached to these proteins. USP11 is implicated in several X-linked retinal diseases and, due to its ability to deubiquitinate BRCA2, may play a role in tumor suppression.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 266-311 of Human USP11.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P51784
Uniprot	P51784
Weight	110 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: USP11 polyclonal antibody detects endogenous levels of USP11 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303172	BS5973	50µl	$190.44		Add to Cart
BHA11303172	BS5973	100µl	$294.44		Add to Cart

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