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Home / Antibodies

Anti-UBE2D2 Antibody BHA11303169

SKU : BHA11303169

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Mfr.No.	BS5969
Alternative Names	Ubiquitin-conjugating enzyme E2 D2 ; Ubiquitin carrier protein D2 ; Ubiquitin-conjugating enzyme E2(17)KB 2 ; Ubiquitin-conjugating enzyme E2-17 kDa 2 ; Ubiquitin-protein ligase D2 ; p53-regulated ubiquitin-conjugating enzyme 1 ; PUBC1 ; UBC4 ; UBC5B ; UBCH4 ; UBCH5B
Categories	Primary Antibodies
Chromosome Location	5q31.2
Clonality	polyclonal
Description	Rub1 shares 53% homology with ubiquitin and requires activation via the E2 proteins, including Ula1, Uba3 and Ubc12, in order to conjugate to substrates directed to different proteolytic systems. UBE2D2 catalyzes ubiquitination of IkBa in a phosphorylation and SCFB-TRCP dependent manner. In this particular reaction, E1 first transfers ubiquitin to the E2 component UBE2D2, and UBE2D2 then associates with E3 ligase, which conjugates the poly-ubiquitin chain on a target protein. In this fashion, the chain tags the IkBa for degradation by a proteasome thus lifting the inhibitory effect of IkBa on NFkB and allowing NFkB to enter the nucleus.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 102-147 of Human UBE2D2.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P62837
Uniprot	P62837
Weight	17 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: UBE2D2 polyclonal antibody detects endogenous levels of UBE2D2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, ICC

Description

WB ; ICC

Dilution

WB	1:500-1:1000
ICC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303169	BS5969	50µl	$190.44		Add to Cart
BHA11303169	BS5969	100µl	$294.44		Add to Cart

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