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Home / Antibodies

Anti-SMAD3/SMAD2 Antibody BHA11304750

SKU : BHA11304750

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Mfr.No.	BS64092
Alternative Names	Mothers against decapentaplegic homolog 2 ; MAD homolog 2 ; Mothers against DPP homolog 2 ; JV18-1 ; Mad-related protein 2 ; hMAD-2 ; SMAD family member 2 ; SMAD 2 ; Smad2 ; hSMAD2 ; MADH2 ; MADR2 ; Mothers against decapentaplegic homolog 3 ; MAD homolog 3 ; Mad3 ; Mothers against DPP homolog 3 ; hMAD-3 ; JV15-2 ; SMAD family member 3 ; SMAD 3 ; Smad3 ; hSMAD3 ; MADH3
Antigen	SMAD3/SMAD2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of TGF∫/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF∫ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGF∫ signaling by interfering with TGF∫-mediated phosphorylation of other Smad proteins.
Host	Rabbit
Immunogen	Synthetic peptide derived from humanSMAD2/3 around the acetylated at Lys19.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q15796; P84022
Uniprot	Q15796; P84022
Weight	89 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. Specificity: SMAD2/3 (Acetyl-K19) polyclonal antibody detects endogenous levels of SMAD2/3 protein only when acetylated at Lys19.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304750	BS64092	50µl	$190.44		Add to Cart
BHA11304750	BS64092	100µl	$294.44		Add to Cart

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