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Home / Antibodies

Anti-SLC9A7 Antibody BHA11301903

SKU : BHA11301903

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Mfr.No.	BS3400
Alternative Names	Sodium/hydrogen exchanger 7 ; Na(+)/H(+) exchanger 7 ; NHE-7 ; Solute carrier family 9 member 7 ; SLC9A7 ; NHE7
Categories	Primary Antibodies
Chromosome Location	Xp11.3
Clonality	polyclonal
Description	Na+/H+ exchangers (NHE) of mammalian cells are plasma membrane intrinsic proteins mediating exchange of N+ and H+ ions in various tissues. The NHE catalyzes the electroneural transport of extracellular Na+ for intracellular H+. They play a major role in regulation of intracellular pH (pHi) in addition to trans-cellular absorption of Na+, cell volume regulation and possibly in cell proliferation. These primary functions of the Na+/H+ exchanger have been related to many pathophysiological states, include hypertension, organ growth and hypertrophy, regression of cancer and renal intestinal disorders. At least 7 NHE isoforms (NHE1-7) have been cloned so far. They are all similar in their primary structure and predicted to have 10-12 transmembrane domains. The C-terminal domain of NHEs are predicted to be intracellular. NHE7 (human 725 aa, chromosome Xp11.4) is ubiquitously expressed, and predominantly localizes to the trans-golgi network. NHE7 mediates the influx of Na+ or K+ in exchange for H+. It is ~70% related to NHE6 but relatively less (~25%) homologous with other NHEs.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 530-582 of Human NHE-7.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q96T83
Uniprot	Q96T83
Weight	80 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: NHE-7 (D566) polyclonal antibody detects endogenous levels of NHE-7 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301903	BS3400	50µl	$190.44		Add to Cart
BHA11301903	BS3400	100µl	$294.44		Add to Cart

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