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Home / Antibodies

Anti-SLC6A8 Antibody BHA11303138

SKU : BHA11303138

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Mfr.No.	BS5934
Alternative Names	Sodium- and chloride-dependent creatine transporter 1 ; CT1 ; Creatine transporter 1 ; Solute carrier family 6 member 8
Categories	Primary Antibodies
Chromosome Location	Xq28
Clonality	polyclonal
Description	SLC6A8 (solute carrier family 6 member 8), also known as CT1 (creatine transporter 1), CRT or CRTR, is a 635 amino acid multi-pass plasma membrane protein that belongs to the sodium/neurotransporter (SNF) family. Expressed in a variety of tissues including kidney, skeletal muscle, heart, brain, prostate, testis and colon, SLC6A8 functions to transport creatine into and out of cells, specifically those found in brain and muscle tissue. Creatine, an organic acid, occurs naturally and is essential for supplying the energy needed for proper muscle and nerve function. Defects in the gene encoding SLC6A8 lead to cerebral creatine deficiency and are the cause of X-linked creatine deficiency syndrome, a rare disorder characterized by facial anomalies, seizures and mental retardation. Multiple isoforms of SLC6A8 exist due to alternative splicing events.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 590-635 of Human SLC6A8.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P48029
Uniprot	P48029
Weight	70 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: SLC6A8 polyclonal antibody detects endogenous levels of SLC6A8 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303138	BS5934	50µl	$190.44		Add to Cart
BHA11303138	BS5934	100µl	$294.44		Add to Cart

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