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Home / Antibodies

Anti-SLC22A3 Antibody BHA11301891

SKU : BHA11301891

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Mfr.No.	BS3359
Alternative Names	Solute carrier family 22 member 3 ; Extraneuronal monoamine transporter ; EMT ; Organic cation transporter 3 ; SLC22A3 ; EMTH ; OCT3
Antigen	SLC22A3
Categories	Primary Antibodies
Chromosome Location	6q25.3
Clonality	polyclonal
Description	Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from a wide range of tissues, where they function in the elimination of endogenous amines, cationic drugs and other xenobiotics. The structure of OCTs consists of a 12-transmembrane-domain structure and a large extracellular hydrophilic loop. In humans, OCT1 is primarily expressed in the liver while OCT2 is expressed in the kidney. OCT3 is expressed in the placenta, skeletal muscle, prostate, aorta and liver. OCT3, also known as extraneuronal monoamine transporter, is widely expressed in different regions of the brain including the hippocampus, cerebellum and cerebral cortex. OCT3 mediates the uptake of several neuroactive agents, including dopamine, and may play an important role in the disposition of neurotransmitters and cationic neurotoxins in the brain.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 281-330 of Human SLC22A3.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O75751
Uniprot	O75751
Weight	61 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: SLC22A3 (Q306) polyclonal antibody detects endogenous levels of SLC22A3 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301891	BS3359	50µl	$190.44		Add to Cart
BHA11301891	BS3359	100µl	$294.44		Add to Cart

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