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Home / Primary Antibodies / IHC Antibodies

Anti-SGK1 Antibody BHA11302514

SKU : BHA11302514

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Mfr.No.	BS4249
Alternative Names	Serine/threonine protein kinase SGK ; Serine/threonine protein kinase Sgk1 ; Serine/threonine-protein kinase Sgk1 ; Serum and glucocorticoid regulated kinase ; Serum/glucocorticoid regulated kinase 1 ; Serum/glucocorticoid regulated kinase ; Serum/glucocorticoid-regulated kinase 1 ; SGK 1 ; SGK ; SGK1 ; SGK1
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Serum- and glucocorticoid-regulated kinase (SGK), also known as SGK1, is a serine/threonine protein kinase and a member of the "AGC" subfamily, which includes protein kinases A, G, and C. SGK plays an important role in activating certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. SGK contains a catalytic domain, which is most similar to Akt1. SGK is a downstream target of PI 3-kinase-stimulated growth factor signaling, with 3-phosphoinositide-dependent protein kinase 1 (PDK1) capable of phosphorylating the activation-loop of SGK at Threonine-256.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human SGK1 around the phosphorylation site of Serine 422.
Modification	phospho-S422
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	O00141
Uniprot	O00141
Weight	54 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-SGK (S422) polyclonal antibody detects endogenous levels of SGK protein only when phosphorylated at Ser422
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302514	BS4249	50µl	$199.33		Add to Cart
BHA11302514	BS4249	100µl	$314.89		Add to Cart

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