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Home / Antibodies

Anti-SFTPA1 Antibody BHA11303693

SKU : BHA11303693

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Mfr.No.	BS60561
Alternative Names	Pulmonary surfactant-associated protein A1 ; PSP-A ; PSPA ; SP-A ; SP-A1 ; 35 kDa pulmonary surfactant-associated protein ; Alveolar proteinosis protein ; Collectin-4 ; SFTPA1 ; COLEC4 ; PSAP ; SFTP1 ; SFTPA ; SFTPA1B
Antigen	SFTPA1
Categories	Primary Antibodies
Chromosome Location	10q22.3
Clonality	polyclonal
Description	Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials. In humans, there are four SFTPA genes localized on chromosome 10. Research indicates that the SFTPA genes are differentially regulated by glucocorticoids, insulin, and cAMP. Expression of two highly similar SP-A proteins, SP-A1 and SP-A2 has been confirmed.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human SFTPA1
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q8IWL2
Uniprot	Q8IWL2
Weight	26 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: SFTPA1 polyclonal antibody detects endogenous levels of SFTPA1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303693	BS60561	50µl	$190.44		Add to Cart
BHA11303693	BS60561	100µl	$294.44		Add to Cart

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