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Home / Antibodies

Anti-S1PR3 Antibody BHA11301812

SKU : BHA11301812

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Mfr.No.	BS3161
Alternative Names	Sphingosine 1-phosphate receptor 3 ; S1P receptor 3 ; S1P3 ; Endothelial differentiation G-protein coupled receptor 3 ; Sphingosine 1-phosphate receptor Edg-3 ; S1P receptor Edg-3 ; S1PR3 ; EDG3
Categories	Primary Antibodies
Chromosome Location	9q22.1
Clonality	polyclonal
Description	EDG3 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG3 is expressed in heart, placenta, kidney, and liver tissue.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 10-51 of Human EDG-3.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q99500
Uniprot	Q99500
Weight	42 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: EDG-3 (L41) polyclonal antibody detects endogenous levels of EDG-3 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:1000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301812	BS3161	50µl	$190.44		Add to Cart
BHA11301812	BS3161	100µl	$294.44		Add to Cart

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