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Home / Antibodies

Anti-RCAN1 Antibody BHA11302928

SKU : BHA11302928

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Mfr.No.	BS5702
Alternative Names	Calcipressin 1 ; Calcipressin1 ; Adapt78 ; Down syndrome critical region protein 1 ; Myocyte-enriched calcineurin-interacting protein 1 ; MCIP1 ; Regulator of calcineurin 1 ; RCAN1 ; ADAPT78 ; CSP1 ; DSC1 ; DSCR1
Antigen	RCAN1
Categories	Primary Antibodies
Chromosome Location	21q22.12
Clonality	polyclonal
Description	Calcipressin-1, also known as DSCR1 (Down syndrome critical region 1), Adapt78, MCIP1 (myocyte-enriched calcineurin-interacting protein 1) or regulator of calcineurin 1, is a 252 amino acid protein that belongs to the RCAN family and exists as four alternatively spliced isoforms. Abundantly expressed in skeletal muscle, brain and heart, DSCR 1 is thought to influence cardiac and nervous system development. Overexpression of DSCR1 may play a role in the pathogenesis of Down syndrome. DSCR1 interacts with Raf-1 and has been observed to inhibit calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. The gene encoding DSCR 1 maps to human chromosome 21, which which houses approximately 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer's disease, amyotrophic lateral sclerosis and, most notably, Down syndrome (also known as trisomy 21).
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to the 207-252 of Human Calcipressin-1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P53805
Uniprot	P53805
Weight	23 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: Calcipressin-1 polyclonal antibody detects endogenous levels of Calcipressin-1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302928	BS5702	50µl	$190.44		Add to Cart
BHA11302928	BS5702	100µl	$294.44		Add to Cart

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