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Home / Antibodies

Anti-PRSS8 Antibody BHA11303713

SKU : BHA11303713

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Mfr.No.	BS60585
Alternative Names	Prostasin ; Channel-activating protease 1 ; CAP1 ; Serine protease 8 ; PRSS8
Categories	Primary Antibodies
Chromosome Location	16p11.2
Clonality	polyclonal
Description	Prostasin, a serine protease first identified in prostate tissue, activates epithelial sodium channels in a variety of tissues. Though typically a membrane-anchored protein, free prostasin is also found in physiologic fluids and tissue culture media, indicating a mechanism for secretion from the cells as well. Aprotinin and other protease inhibitors suppress the channel-activating capacity of prostasin, while aldosterone increases prostasin expression and stimulates sodium uptake. In addition, DNA methylation negatively correlates with prostasin expression in cancer cells, while enforced reexpression decreases invasiveness as well as metastatic potential, implying that prostasin activity reflects epithelial cell physiology.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human PRSS8
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q16651
Uniprot	Q16651
Weight	36 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: PRSS8 polyclonal antibody detects endogenous levels of PRSS8 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303713	BS60585	50µl	$190.44		Add to Cart
BHA11303713	BS60585	100µl	$294.44		Add to Cart

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