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Home / Antibodies

Anti-PRRX1 Antibody BHA11303077

SKU : BHA11303077

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Mfr.No.	BS5867
Alternative Names	Paired mesoderm homeobox protein 1 ; Homeobox protein PHOX1 ; Paired-related homeobox protein 1 ; PRX-1 ; PMX1
Categories	Primary Antibodies
Chromosome Location	1q24.2
Clonality	polyclonal
Description	The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. PRX1 (paired related homeobox 1), also known as PRRX1, PMX1 or PHOX1, is a 245 amino acid protein that contains one OAR domain and one homeobox DNA-binding domain and belongs to the paired homeobox family. Localized to the nucleus, PRX1 functions as a transcriptional co-activator that enhances the DNA-binding activity of serum response factor (SRF), thereby mediating the induction of SRF-dependent gene expression by growth and differentiation factors. Additionally, PRX1 regulates the transcriptional activities of creatine kinase-M (muscle), thereby playing a role in the establishment of mesodermal muscle types. PRX1 exists as two alternatively spliced isoforms, designated PMX1-A and PMX1-B.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 100-145 of Human PRRX1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P54821
Uniprot	P54821
Weight	27 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: PRRX1 polyclonal antibody detects endogenous levels of PRRX1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, ICC

Description

WB ; ICC

Dilution

WB	1:500-1:1000
ICC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303077	BS5867	50µl	$190.44		Add to Cart
BHA11303077	BS5867	100µl	$294.44		Add to Cart

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