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Home / Primary Antibodies / IHC Antibodies

Anti-PRKCZ/PRKCQ/PRKCH/PRKCG/PRKCE/PRKCD/PRKCB/PRKCA Antibody BHA11302559

SKU : BHA11302559

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Mfr.No.	BS4348
Alternative Names	Protein kinase C alpha type ; PKC-A ; PKC-alpha ; PRKCA ; PKCA ; PRKACA ; Protein kinase C beta type ; PKC-B ; PKC-beta ; PKCB ; PRKCB1 ; PRKCB ; Protein kinase C gamma type ; PKC-gamma ; PKCG ; PRKCG ; Protein kinase C delta type ; Tyrosine-protein kinase PRKCD ; nPKC-delta ; Sphingosine-dependent protein kinase-1 ; SDK1 ; PRKCD ; Protein kinase C epsilon type ; nPKC-epsilon ; PRKCE ; PKCE ; Protein kinase C zeta type ; nPKC-zeta ; PRKCZ ; PKC2 ; PKC zeta ; Protein kinase C theta type ; nPKC-theta ; PRKCQ ; PRKCT
Antigen	PRKCZ/PRKCQ/PRKCH/PRKCG/PRKCE/PRKCD/PRKCB/PRKCA
Categories	Primary Antibodies
Clonality	polyclonal
Description	Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms (δ, ε, ζ, η and θ). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC δ and ε are independent of Ca2+.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human PKC-pan around the phosphorylation site of Threonine 497.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P17252/P05771/Q05655/Q02156/P05129/P24723/Q04759/Q05513
Uniprot	P17252/P05771/Q05655/Q02156/P05129/P24723/Q04759/Q05513
Weight	; 75 to 88 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-PKC-pan (αT497) polyclonal antibody detects endogenous levels of PKC PKC α, β I, β II, γ, δ, ε, η, ζ and θ isoforms only when phosphorylated at a residue homologous to threonine 497 of human PKCα.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302559	BS4348	50µl	$199.33		Add to Cart
BHA11302559	BS4348	100µl	$314.89		Add to Cart

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