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Home / Antibodies

Anti-PPP4R1 Antibody BHA11303861

SKU : BHA11303861

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Mfr.No.	BS60748
Alternative Names	Serine/threonine-protein phosphatase 4 regulatory subunit 1 ; PPP4R1 ; MEG1 ; PP4R1
Antigen	PPP4R1
Categories	Primary Antibodies
Clonality	polyclonal
Description	In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Protein phosphatase 4 (PP4) is comprised of different regulatory subunits that exhibit mutually exclusive interactions with the PP4 catalytic subunit, PPX. PP4R1, also known as PPP4R1 or PP4(Rmeg), is regulatory subunit 1 of protein phosphatase 4. It is ubiquitously expressed and can form a binary complex with PPX that negatively regulates the activity of HDAC3. PP4 is required for cell growth, nucleation and the stabilization of microtubules during cell division. This suggests that PP4R1 participates in the regulation of mitosis.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human PPP4R1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q8TF05
Uniprot	Q8TF05
Weight	107 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: PPP4R1 polyclonal antibody detects endogenous levels of PPP4R1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303861	BS60748	50µl	$190.44		Add to Cart
BHA11303861	BS60748	100µl	$294.44		Add to Cart

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