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Home / Antibodies

Anti-POLR2I Antibody BHA11303301

SKU : BHA11303301

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Mfr.No.	BS60145
Alternative Names	DNA-directed RNA polymerase II subunit RPB9 ; RNA polymerase II subunit B9 ; DNA-directed RNA polymerase II subunit I ; RNA polymerase II 14.5 kDa subunit ; RPB14.5
Antigen	POLR2I
Categories	Primary Antibodies
Chromosome Location	19q13.12
Clonality	polyclonal
Description	RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. POLR2I (polymerase (RNA) II (DNA directed) polypeptide I), also known as RPB9 or hRPB14.5, is a 125 amino acid nuclear protein belonging to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. Component of RNA polymerase II, POLR2I catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR2I is part of the upper jaw surrounding the central large cleft and is thought to grab the incoming DNA template.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human POLR2I.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P36954
Uniprot	P36954
Weight	14 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: POLR2I polyclonal antibody detects endogenous levels of POLR2I protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303301	BS60145	50µl	$190.44		Add to Cart
BHA11303301	BS60145	100µl	$294.44		Add to Cart

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