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Home / Primary Antibodies / IHC Antibodies

Anti-PIK3R3/PIK3R1 Antibody BHA11300027

SKU : BHA11300027

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Mfr.No.	AP0230
Alternative Names	Phosphatidylinositol 3-kinase regulatory subunit alpha ; PI3-kinase regulatory subunit alpha ; PI3K regulatory subunit alpha ; PtdIns-3-kinase regulatory subunit alpha ; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha ; PI3-kinase subunit p85-alpha ; PtdIns-3-kinase regulatory subunit p85-alpha ; PIK3R1 ; GRB1 ; Phosphatidylinositol 3-kinase regulatory subunit gamma ; PI3-kinase regulatory subunit gamma ; PI3K regulatory subunit gamma ; PtdIns-3-kinase regulatory subunit gamma ; Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma ; PI3-kinase subunit p55-gamma ; PtdIns-3-kinase regulatory subunit p55-gamma ; p55PIK ; PIK3R3
Categories	Primary Antibodies
Clonality	polyclonal
Description	The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 430-480 of Human PI3K p85α.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P27986/Q92569
Uniprot	P27986/Q92569
Weight	55, 85 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: PI3K p85α/p55γ (Y467/199) polyclonal antibody detects endogenous levels of PI3-kinase p85α protein.This antibody also detects PI3K p55γ protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300027	AP0230	50µl	$190.44		Add to Cart
BHA11300027	AP0230	100µl	$294.44		Add to Cart

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