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Home / Primary Antibodies / IHC Antibodies

Anti-PGC Antibody BHA11302131

SKU : BHA11302131

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Mfr.No.	BS3685
Alternative Names	Pepsinogen C ; PGC ; Gastricsin
Antigen	PGC
Categories	Primary Antibodies
Chromosome Location	6p21.1
Clonality	polyclonal
Description	Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 280-330 of Human Pepsin C.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P20142
Uniprot	P20142
Weight	42 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Pepsin C (F306) polyclonal antibody detects endogenous levels of Pepsin C protein .
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302131	BS3685	50µl	$190.44		Add to Cart
BHA11302131	BS3685	100µl	$294.44		Add to Cart

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