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Home / Antibodies

Anti-NKX2-8 Antibody BHA11308827

SKU : BHA11308827

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Mfr.No.	BS9251
Alternative Names	NK 2 homolog 8 ; NK 2 homolog H ; NK2 homeobox 8 ; NK2 transcription factor related ; locus 8 ; Nkx2 9 ; Nkx2-8 ; NKX2.8 ; NKX2G ; NKX2H
Categories	Primary Antibodies
Chromosome Location	14q13.3
Clonality	polyclonal
Description	Members of the NK-2 family of homeodomain proteins, which include Nkx-2.2, Nkx-2.5, Nkx-2.6 and Nkx-2.8, are key regulators of growth and development in several tissues, including brain, heart and pancreas. Nkx-2.2 is responsible for directing ventral neuronal patterning in response to graded Shh signaling. Nkx-2.5, also designated cardiac specific homeobox protein (Csx), is a homolog of the Drosophila tinman protein and is essential for normal cardiovascular development. Nkx-2.6, also a homolog of the Drosophila tinman protein, is expressed in the caudal pharyngeal pouches, the caudal heart progenitors, the sinus venosus, the outflow tract of the heart and in a short segment of the gut between stages E8.5 and E10.5 of embryogenesis. Nkx-2.8, also designated NK-2 homolog H, NKX2H or Nkx-2.9, is a nuclear protein that contains one homeobox DNA-binding domain, indicating a possible role in development.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 11-60 of Human Nkx-2.8.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O15522
Uniprot	O15522
Weight	28 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Nkx-2.8 (P37) polyclonal antibody detects endogenous levels of Nkx-2.8 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308827	BS9251	50µl	$190.44		Add to Cart
BHA11308827	BS9251	100µl	$294.44		Add to Cart

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