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Home / Antibodies

Anti-NFE2L3 Antibody BHA11308835

SKU : BHA11308835

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Mfr.No.	BS9275
Alternative Names	Nuclear factor erythroid 2-related factor 3 ; NF-E2-related factor 3 ; NFE2-related factor 3 ; Nuclear factor, erythroid derived 2, like 3 ; NFE2L3 ; NRF3
Categories	Primary Antibodies
Chromosome Location	7p15.2
Clonality	polyclonal
Description	Nrf3 (nuclear factor (erythroid-derived 2)-like 3, NFE2L3, NF-E2-related factor 3, NRF3) is a transcription factor that influences placental gene expression and development. Nrf3 contains a Cap'n'collar (CNC)-type basic leucine zipper (bZIP) domain, and belongs to the CNC gene family. CNC genes play important roles in development, differentiation, oncogenesis, and stress signaling. Nrf3 protein is detectable in primary placental cytotrophoblasts. The human choriocarcinoma cell lines BeWo and JAR from trophoblastic tumors of the placenta express Nrf3 transcripts. Nrf3/MAFG heterodimers recognize nuclear factor-erythroid 2/Maf recognition element-type DNA-binding motifs. Keratinocyte growth factor (KGF)-regulates Nrf3-dependent gene expression during cutaneous wound repair.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 500-520 of Human Nrf3.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9Y4A8
Uniprot	Q9Y4A8
Weight	76 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Nrf3 (D530) polyclonal antibody detects endogenous levels of Nrf3 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308835	BS9275	50µl	$190.44		Add to Cart
BHA11308835	BS9275	100µl	$294.44		Add to Cart

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