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Home / Antibodies

Anti-NDRG2 Antibody BHA11304142

SKU : BHA11304142

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Mfr.No.	BS61243
Alternative Names	Protein NDRG2 ; N-myc downstream-regulated gene 2 protein ; Protein Syld709613 ; NDRG2 ; KIAA1248 ; SYLD
Antigen	NDRG2
Categories	Primary Antibodies
Chromosome Location	14q11.2
Clonality	polyclonal
Description	The N-myc downstream regulated gene (NDRG) family is comprised of four members, namely NDRG1, NDRG2, NDRG3 and NDRG4, all of which share 57-65% homology. NDRG2 (NDRG family member 2), also known as SYLD, is a 371 amino acid protein that localizes to both the cytoplasm and the perinuclear region in neurons. Expressed at high levels in heart, brain, dendritic cells, salivary gland and skeletal muscle and at lower levels in liver and kidney, NDRG2 is thought to be involved in dendritic and neuronal cell differentiation and outgrowth. Additionally, NDRG2 expression is downregulated in a variety of carcinomas, including liver cancer, pancreatic cancer and meningioma, suggesting a possible role for NDRG2 in tumor suppression. NDRG2 is found in brain lesions of Alzheimer Disease (AD)-affected patients and is thought to be associated with the progression of AD. Five isoforms of NDRG2 exist due to alternative splicing events.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human NDRG2.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9UN36
Uniprot	Q9UN36
Weight	41 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. Specificity: NDRG2 polyclonal antibody detects endogenous levels of NDRG2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304142	BS61243	50µl	$190.44		Add to Cart
BHA11304142	BS61243	100µl	$294.44		Add to Cart

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