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Home / Antibodies

Anti-NDFIP1 Antibody BHA11304539

SKU : BHA11304539

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Mfr.No.	BS61770
Alternative Names	NEDD4 family-interacting protein 1 ; Breast cancer-associated protein SGA-1M ; NEDD4 WW domain-binding protein 5 ; Putative MAPK-activating protein PM13 ; Putative NF-kappa-B-activating protein 164 ; Putative NFKB and MAPK-activating protein ; NDFIP1 ; N4WBP5 ; PSEC0192 ; PSEC0223
Antigen	NDFIP1
Categories	Primary Antibodies
Chromosome Location	5q31.3
Clonality	polyclonal
Description	Nedd4 family interacting protein-1 (Ndfip1), also referred to as N4WBP5, is a member of a family of highly conserved proteins. It has three transmembrane domains in its carboxy terminal and two PY motifs in its amino terminal. Ndfip1 is a 221 amino acid, Golgi-associated protein that may play a role in Golgi structure and function. Ndfip1 binds the WW domains of a number of Nedd4 family members called HECT-type E3 ubiquitin ligases. Ndfip1 is strongly expressed in surviving neurons around a site of injury. This suggests that ubiquitination may be a possible survival strategy and Ndfip1 may act as a neuroprotective protein. Ndfip1 may also have an effect on the function of Itch, another E3 ubiquitin ligase. Expression of Ndfip1 and its association with Itch may be promoted by T cell activation. Mice lacking Ndfip1 exhibit inactivation of Itch and accumulation of JunB causing them to die prematurely with severe skin and lung inflammation.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 170-220 of Human NDFIP1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9BT67
Uniprot	Q9BT67
Weight	24 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. Specificity: NDFIP1 polyclonal antibody detects endogenous levels of NDFIP1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304539	BS61770	50µl	$190.44		Add to Cart
BHA11304539	BS61770	100µl	$294.44		Add to Cart

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