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Home / Primary Antibodies / Recombinant Antibodies

Anti-NAGA Antibody BHA11306183

SKU : BHA11306183

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Mfr.No.	BS71378
Alternative Names	Alpha-galactosidase B ; α-galactosidase B ; galactosidaseαB ; galactosidase-αB
Antigen	NAGA
Categories	Primary Antibodies
Chromosome Location	22q13.2
Clonality	polyclonal
Description	NAGA (N-acetylgalactosaminidase, α), also known as α-galactosidase B or GALB, is a 411 lysosomal protein belonging to the glycosyl hydrolase 27 family that may exist as a homodimer and plays a critical role in glycolipid breakdown. NAGA encodes α-N-acetylgalactosaminidase, a lysosomal enzyme, which cleaves α-N-acetylgalactosaminyl groups from glycoconjugates. Mapping to human chromosome 22q13.2, NAGA defects are the cause of an autosomal recessive disorder with three phenotypes, known as Schindler disease (types I, II and III) or NAGA deficiency (types I, II and III). Characterized by neurologic manifestations that range in severity, Schindler disease type I is the most severe form, followed by type III, which may have mild-to-moderate effects. Schindler disease type II, also known as Kanzaki disease, is characterized by mild intellectual impairment and angiokeratoma corporis diffusum.
Host	Rabbit
Immunogen	Recombinant protein of human NAGA.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P17050
Uniprot	P17050
Weight	47 kDa

Description	Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Specificity: NAGA polyclonal antibody detects endogenous levels of NAGA protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11306183	BS71378	50µl	$234.89		Add to Cart
BHA11306183	BS71378	100µl	$368.22		Add to Cart

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