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Home / Antibodies

Anti-MED22 Antibody BHA11303328

SKU : BHA11303328

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Mfr.No.	BS60173
Alternative Names	Mediator of RNA polymerase II transcription subunit 22 ; Mediator complex subunit 22 ; Surfeit locus protein 5 ; Surf-5 ; MED22 ; SURF5
Antigen	MED22
Categories	Primary Antibodies
Chromosome Location	9q34.2
Clonality	polyclonal
Description	Med22 is a subunit of the RNA polymerase II (Pol II) transcriptional mediator complex. The mediator complex is a coactivator involved in the regulated transcription of Pol II-dependent genes. Functioning as a bridge to convey information from gene-specific regulatory proteins to the basal Pol II transcription machinery, the mediator complex is recruited to promoter regions by directly interacting with regulatory proteins. The mediator complex also serves as a scaffold for the assembly of a functional pre-initiation complex with Pol II and other general transcription factors. Med22 (Mediator complex subunit 22), also known as SURF5 (Surfeit locus protein 5), is a ubiquitously expressed 200 amino acid nuclear protein that is one of several components of the mediator complex. There are two isoforms of Med22 that are produced as a result of alternative splicing events.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human MED22.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q15528
Uniprot	Q15528
Weight	22 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: MED22 polyclonal antibody detects endogenous levels of MED22 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303328	BS60173	50µl	$190.44		Add to Cart
BHA11303328	BS60173	100µl	$294.44		Add to Cart

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