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Home / Primary Antibodies

Anti-MBD2 Antibody

SKU : BHA10902455

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y058161
Categories	Primary Antibodies
Cellular Localization	Nucleus
Clonality	polyclonal
Description	DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.
Host	Rabbit
Immunogen	Synthetic peptide conjugated to KLH
Isotype	IgG
Quantity	100 µl
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Description	Specificity: Not yet tested in other species.
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, ELISA

Description

For research use only
Peptide ELISA titer: 1:40,000-1:80,000
Western blot analysis: 1:200-500
Optimal dilutions/concentrations should be determined by the end use, WB ; ELISA

Dilution

ELISA	1:40,000-1:80,000
WB	1:200-500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10902455	Y058161	100 ul	$217.50		Add to Cart

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