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Home / Antibodies

Anti-MAP1LC3C/MAP1LC3A/MAP1LC3B Antibody BHA11300149

SKU : BHA11300149

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Mfr.No.	AP1013
Alternative Names	Microtubule-associated protein 1 light chain 3 beta ; MAP1LC3B ; MAP1ALC3 ; LC3-I ; LC3-II ; LC3I ; LC3II
Categories	Primary Antibodies
Clonality	polyclonal
Description	Two forms of LC3β , the cytosolic LC3-I and the membrane-bound LC3-II, are produced post-translationally. LC3-I is formed by the removal of the C-terminal 22 amino acids from newly synthesized LC3β , followed by the conversion of a fraction of LC3-I into LC3-II. LC3 enhances fibronectin mRNA translation in ductus arteriosus cells through association with 60S ribosomes and binding to an AU-rich element in the 3’ untranslated region of fibronectin mRNA. This facilitates sorting of fibronectin mRNA onto rough endoplasmic reticulum and translation. MAP LC3β may also be involved in formation of autophagosomal vacuoles. It is expressed primarily in heart, testis, brain and skeletal muscle.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human LC3.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9GZQ8/Q9H492/Q9BXW4
Uniprot	Q9GZQ8/Q9H492/Q9BXW4
Weight	15 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. Specificity: LC3 (T50) polyclonal antibody detects endogenous levels of LC3-I and LC3-II protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300149	AP1013	50µl	$190.44		Add to Cart
BHA11300149	AP1013	100µl	$294.44		Add to Cart

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