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Home / Antibodies

Anti-LY75 Antibody BHA11302889

SKU : BHA11302889

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Mfr.No.	BS5653
Alternative Names	Lymphocyte antigen 75 ; Ly-75 ; C-type lectin domain family 13 member B ; DEC-205 ; gp200-MR6 ; CD205 ; CLEC13B ; DEC205
Antigen	LY75
Categories	Primary Antibodies
Chromosome Location	2q24.2
Clonality	polyclonal
Description	DEC-205 (LY75, lymphocyte antigen 75, GP200-MR6) is a 1,695 residue (mature form) multilectin receptor that belongs to the MMR (macrophage mannose receptor) family of multidomain molecules. MMR family molecules mediate membrane receptor targeting to endosomes or lysosomes rich in major histocompatibility complex class II (MHC II) products. Expressed in mature dendritic cells (DC), DEC-205 contains an extracellular N-terminal cysteine-rich domain, a fibronectin type II domain, ten C-type carbohydrate recognition domains, a single transmembrane region and a small cytoplasmic C-terminal domain (31 amino acids) containing a tyrosine at 1679. DEC-205 elicits either an agonistic or antagonistic effect on IL-4 function, which is demonstrated by the ability of DEC-205 to imitate IL-4-induced maturation of epithelium or to inhibit IL-4-induced proliferation of T cells, respectively.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 509-554 of Human LY75.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O60449
Uniprot	O60449
Weight	198 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: LY75 polyclonal antibody detects endogenous levels of LY75 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302889	BS5653	50µl	$190.44		Add to Cart
BHA11302889	BS5653	100µl	$294.44		Add to Cart

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