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Home / Primary Antibodies / IHC Antibodies

Anti-KRT16/KRT14 Antibody BHA11300370

SKU : BHA11300370

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Mfr.No.	BS1200
Alternative Names	Keratin, type I cytoskeletal 14 ; Cytokeratin-14 ; Short name=CK-14 ; Keratin-14 ; Short name=K14 ; KRT14 ; CK-14 ; CK 14 ; CK14 ; Cytokeratin-14 ; Cytokeratin 14 ; Cytokeratin14 ; Keratin, type I cytoskeletal 16 ; Cytokeratin-16 ; Short name=CK-16 ; Keratin-16 ; Short name=K16 ; KRT16 ; KRT16A ; CK-16 ; CK 16 ; CK16 ; Cytokeratin-16 ; Cytokeratin 16 ; Cytokeratin16
Antigen	KRT16/KRT14
Categories	Primary Antibodies
Clonality	polyclonal
Description	In Bowen’s disease, the characteristic malignancy of the epidermis exhibits distinct expression patterns of Cytokeratin 14. Mutations in the gene encoding human Cytokeratin 14 lead to epidermolysis bullosa simplex, an inheritied skin disorder characterized by skin blistering due to basal keratinocyte fragility.Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in noninvasive breast carcinomas and normal breast tissue. Mutations in the Cytokeratin 16 gene cause various diseases, including pachyonychia congenita type 1 (PC1), nonepidermolytic palmoplantar keratoderma (NEPPK) and unilateral palmoplantar verrucous nevus (UPVN).
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to the N-terminus of Human Cytokeratin 14
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P02533/P08779
Uniprot	P02533/P08779
Weight	52 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Cytokeratin 14/16 (S5) polyclonal antibody detects endogenous levels of Cytokeratin 14 and Cytokeratin 16 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IF

Description

IHC ; IF

Dilution

IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300370	BS1200	50µl	$190.44		Add to Cart
BHA11300370	BS1200	100µl	$294.44		Add to Cart

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