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Home / Antibodies

Anti-ITPKB Antibody BHA11302983

SKU : BHA11302983

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Mfr.No.	BS5765
Alternative Names	Inositol-trisphosphate 3-kinase B ; Inositol 1,4,5-trisphosphate 3-kinase B ; IP3 3-kinase B ; IP3K B ; InsP 3-kinase B ; IP3KB
Categories	Primary Antibodies
Chromosome Location	1q42.12
Clonality	polyclonal
Description	Inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) regulates the level of calcium within the cell by releasing calcium from intracellular stores. Ins(1,4,5)P3 is phosphorylated by inositol 1,4,5-trisphosphate 3-kinase (IP3K) to form inositol 1,3,4,5-tetrakisphosphate (Ins(1,4,5)P4), which is is thought to regulate the influx of calcium across the plasma membrane. IP3K exists as three isoforms, IP3KA, B, and C. IP3KA, the most highly characterized isoform, is expressed in rat brain and testis. IP3KB is expressed in various rat tissues such as lung, thymus, testis, brain, and heart. IP3K activity is stimulated in the presence of calmodulin via phosphorylation by cAMP-dependent protein kinase, protein kinase C, or calcium/calmodulin dependent protein kinase II and, subsequently, mediates the inositol phosphate signaling pathways.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 205-250 of Human ITPKB.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P27987
Uniprot	P27987
Weight	74, 120 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: ITPKB polyclonal antibody detects endogenous levels of ITPKB protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302983	BS5765	50µl	$190.44		Add to Cart
BHA11302983	BS5765	100µl	$294.44		Add to Cart

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