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Home / Antibodies

Anti-ITIH2 Antibody BHA11302985

SKU : BHA11302985

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Mfr.No.	BS5768
Alternative Names	Inter-alpha-trypsin inhibitor heavy chain H2 ; ITI heavy chain H2 ; ITI-HC2 ; Inter-alpha-inhibitor heavy chain 2 ; nter-alpha-trypsin inhibitor complex component II ; Serum-derived hyaluronan-associated protein ; SHAP ; ITIH2 ; IGHEP2
Antigen	ITIH2
Categories	Primary Antibodies
Chromosome Location	10p14
Clonality	polyclonal
Description	The inter-α trypsin inhibitor (ITI) family is a group of structurally related plasma serine protease inhibitors synthesized in the liver and built up from different combinations of three highly homologous heavy chains (ITI-HI, ITI-H2 and ITI-H3) and one light chain (bikunin). A fourth member of the ITI family, ITI-H4 (also known as I α IH4P) harbours a Pro-rich region (PRR) in its c-terminus. ITI (also known as IaI) is a 220 kDa glycoprotein composed of three polypeptides linked by chondroitin sulphate: two heavy chains, ITI-H1 (65 kDa) and ITI-H2 (72 kDa), and bikunin (approx. 30 kDa). Bikunin confers the protease-inhibitor function of ITI. The heavy chains of the ITI family, designated as SHAPs (for serum-derived hyaluronan-associated proteins), bind covalently to hyaluronic acid (HA), resulting in pericellular matrix stabilization. ITI-H1 contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 712-757 of Human ITI-H2.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P19823
Uniprot	P19823
Weight	72, 106 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: ITI-H2 polyclonal antibody detects endogenous levels of mature ITI-H2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302985	BS5768	50µl	$190.44		Add to Cart
BHA11302985	BS5768	100µl	$294.44		Add to Cart

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