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Home / Antibodies

Anti-IL2RA Antibody BHA11303978

SKU : BHA11303978

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Mfr.No.	BS60896
Alternative Names	Interleukin-2 receptor subunit alpha ; IL-2 receptor subunit alpha ; IL-2-RA ; IL-2R subunit alpha ; IL2-RA ; TAC antigen ; p55 ; CD25 ; IL2RA
Antigen	IL2RA
Categories	Primary Antibodies
Chromosome Location	10p15.1
Clonality	polyclonal
Description	The IL-2 receptor is amulticomponentcomplexconsisting of three subunits,α, β and γ, each ofwhich isrequired for high-affinity binding of IL-2. Theαchain functions primarilyin binding IL-2, whereasthe β and γ chainscontribute to IL-2 binding and are essential to IL-2-induced activation ofsignaling pathways leading to T cell growth. Both IL-4R and IL-7R were initially described as single chain, high-affinityligand-binding cytokine receptors. However, it is now well established that the IL-2Rγ chain functions as a second subunit of the high affinityIL-4R and IL-7R receptors. Consequently, the originally described subunits of these latter receptors are nowreferred to asIL-4Rαand IL-7Rα, respectively,while the common subunit isreferred to as γc. Although the common γ chain enhancesligand binding in these three cytokine receptors, it has no capacityto bind these ligands on its own. There is evidence that the γcchain is also a subunit of IL-13R.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human IL2RA.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P01589
Uniprot	P01589
Weight	55 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. Specificity: IL2RA polyclonal antibody detects endogenous levels of IL2RA protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303978	BS60896	50µl	$190.44		Add to Cart
BHA11303978	BS60896	100µl	$294.44		Add to Cart

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