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Home / Antibodies

Anti-IL12B Antibody BHA11301958

SKU : BHA11301958

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Mfr.No.	BS3480
Alternative Names	Interleukin-12 subunit beta ; IL-12B ; Cytotoxic lymphocyte maturation factor 40 kDa subunit ; CLMF p40 ; IL-12 subunit p40 ; NK cell stimulatory factor chain 2 ; NKSF2 ; NKSF2 ; IL12B
Antigen	IL12B
Categories	Primary Antibodies
Chromosome Location	5q33.3
Clonality	polyclonal
Description	IL-12 is secreted by macrophages and human B-lymphoblastoid cells in response to antigenic stimulation. This IL is responsible for the differentiation of naive CD4+ T cells into type 1 helper T cells that produce interferon-γ (IFN-γ). It also activates production of tumor necrosis factor α (TNFα) from T and natural killer (NK) cells, and it inhibits IL-4 mediated suppression of IFN-γ. IL-12 also has anti-angiogenic activity since the production of IFN-γ increases the production of inducible protein-10 (IP-10). IL-12 p40 represents a subunit of IL-12 that is induced by several pathogens. IL-12 p70 is a subunit of IL-12 that is controlled through both the p35 and p40 genes in a cell type-specific fashion.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 245-291 of Human IL-12B.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P29460
Uniprot	P29460
Weight	37 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: IL-12B (V277) polyclonal antibody detects endogenous levels of IL-12B protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301958	BS3480	50µl	$190.44		Add to Cart
BHA11301958	BS3480	100µl	$294.44		Add to Cart

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