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Home / Antibodies

Anti-IKZF2 Antibody BHA11304417

SKU : BHA11304417

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Mfr.No.	BS61657
Alternative Names	Zinc finger protein Helios ; Ikaros family zinc finger protein 2 ; IKZF2 ; HELIOS ; ZNFN1A2
Categories	Primary Antibodies
Chromosome Location	2q34
Clonality	polyclonal
Description	Helios (Ikaros family zinc finger 2, IZKF2) is an Ikaros family transcription factor composed of several zinc fingers that mediate DNA binding and homodimerization or heterodimerization with other Ikaros family proteins. In the hematopoietic system, Helios expression is restricted to T cells and early hematopoietic progenitors. In regulatory T cells, expression of Helios contributes to an anergic phenotype by binding to the IL-2 promoter and suppressing IL-2 transcription. In addition, alteration of the corresponding Helios gene IZKF2 is one hallmark of low-hypodiploid acute lymphoblastic leukemia.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding Human IKZF2.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9UKS7
Uniprot	Q9UKS7
Weight	85 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. Specificity: IKZF2 polyclonal antibody detects endogenous levels of IKZF2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304417	BS61657	50µl	$190.44		Add to Cart
BHA11304417	BS61657	100µl	$294.44		Add to Cart

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