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Home / Antibodies

Anti-IDH2 Antibody BHA11303773

SKU : BHA11303773

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Mfr.No.	BS60645
Alternative Names	Isocitrate dehydrogenase [NADP], mitochondrial ; IDH ; ICD-M ; IDP ; NADP(+)-specific ICDH ; Oxalosuccinate decarboxylase ; IDH2
Antigen	IDH2
Categories	Primary Antibodies
Chromosome Location	15q26.1
Clonality	polyclonal
Description	IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), also designated NADP+-specific ICDH; isocitrate dehydrogenase, mitochondrial; and oxalosuccinate decarboxylase, is a 452 amino acid enzyme encoded by the human gene IDH2. IDH2 belongs to the isocitrate and isopropylmalate dehydrogenases family and contains two nucleotide binding regions. IDH2 is involved in the reduction of NADP+ to NADPH and maintains the supply of glutathione (GSH) in mitochondria. It is believed to play a role in intermediary metabolism and energy production. IDH2 also tightly associates with the pyruvate dehydrogenase complex. IDH2 is found in the mitochondrion as a homodimer and can bind one magnesium or manganese ion per subunit.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human IDH2
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P48735
Uniprot	P48735
Weight	51 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: IDH2 polyclonal antibody detects endogenous levels of IDH2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303773	BS60645	50µl	$190.44		Add to Cart
BHA11303773	BS60645	100µl	$294.44		Add to Cart

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